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IRF6 — MOK
Text-mined interactions from Literome
Talmor et al., Eur J Clin Invest 2008
(Inflammation) :
Results Calcitriol decreased the adhesion molecules expression, as well as the
LPS induced mRNA expressions of
RAGE and IL-6 and LPS induced IL-6 secretion
Sharma et al., Fertil Steril 2010
(Endometriosis...) :
The endometrial-endometriotic stromal cells were isolated from ectopic ( group I ) and eutopic ( group II ) endometrium by established methods, cultured, and stimulated with LPS ( 1 µg/mL ), followed by atorvastatin treatment in a time- and dose dependent manner to investigate the
effects of
LPS on proliferation ( Ki-67 ) and expression of cyclooxygenase-2 (COX-2), vascular endothelial growth factor ( VEGF ), receptor for advanced glycation end products ( RAGE ), extracellular newly identified
RAGE binding protein ( EN-RAGE ), peroxisome proliferator activated receptor-? ( PPAR-? ), and liver X receptor-a ( LXR-a ) genes in endometrial-endometriotic stromal cells and on levels of insulin-like growth factor binding protein-1 ( IGFBP-1 ) and 17ß-E ( 2 ) in endometrial-endometriotic stromal cell culture supernatant
Yamamoto et al., J Immunol 2011
(Shock, Septic) :
LPS increased TNF-a secretion from peritoneal macrophages and an NF-?B promoter-driven luciferase activity through
RAGE
Ramsgaard et al., PloS one 2011
(Pneumonia) :
To study this further, model systems utilizing wild type and RAGE knockout ( KO ) mice were used to determine the
role of
RAGE signaling in
lipopolysaccharide (LPS) and E. coli induced acute pulmonary inflammation
Chakraborty et al., Mol Immunol 2013
:
TLR2, TLR4 or
RAGE knockdown macrophages effectively
inhibited the rHMGB1+PGN or
LPS induced NO synergy