Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Talmor et al., Eur J Clin Invest 2008 (Inflammation) : Results Calcitriol decreased the adhesion molecules expression, as well as the LPS induced mRNA expressions of RAGE and IL-6 and LPS induced IL-6 secretion
Sharma et al., Fertil Steril 2010 (Endometriosis...) : The endometrial-endometriotic stromal cells were isolated from ectopic ( group I ) and eutopic ( group II ) endometrium by established methods, cultured, and stimulated with LPS ( 1 µg/mL ), followed by atorvastatin treatment in a time- and dose dependent manner to investigate the effects of LPS on proliferation ( Ki-67 ) and expression of cyclooxygenase-2 (COX-2), vascular endothelial growth factor ( VEGF ), receptor for advanced glycation end products ( RAGE ), extracellular newly identified RAGE binding protein ( EN-RAGE ), peroxisome proliferator activated receptor-? ( PPAR-? ), and liver X receptor-a ( LXR-a ) genes in endometrial-endometriotic stromal cells and on levels of insulin-like growth factor binding protein-1 ( IGFBP-1 ) and 17ß-E ( 2 ) in endometrial-endometriotic stromal cell culture supernatant
Yamamoto et al., J Immunol 2011 (Shock, Septic) : LPS increased TNF-a secretion from peritoneal macrophages and an NF-?B promoter-driven luciferase activity through RAGE
Ramsgaard et al., PloS one 2011 (Pneumonia) : To study this further, model systems utilizing wild type and RAGE knockout ( KO ) mice were used to determine the role of RAGE signaling in lipopolysaccharide (LPS) and E. coli induced acute pulmonary inflammation
Chakraborty et al., Mol Immunol 2013 : TLR2, TLR4 or RAGE knockdown macrophages effectively inhibited the rHMGB1+PGN or LPS induced NO synergy