Gene interactions and pathways from curated databases and text-mining

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ANG — PTGS2

Text-mined interactions from Literome

Young et al., Circ Res 2000 : Tumor necrosis factor-alpha (TNF-alpha) and angiotensin II (Ang II) induced a transient increase in vascular smooth muscle cell ( VSMC ) cyclooxygenase-2 (COX-2) mRNA accumulation, without affecting COX-1 mRNA levels
Hu et al., J Pharmacol Exp Ther 2002 : ANG II type 1 (AT1) receptors induce increased accumulation of COX-2 , both at the mRNA and protein levels
Jensen et al., American journal of physiology. Renal physiology 2006 (Polyuria...) : Moreover, candesartan treatment attenuated induction of cyclooxygenase 2 (COX-2) expression in the inner medulla, suggesting that COX-2 induction in response to obstruction is regulated by ANG II
Matsuzuka et al., Mol Cell Biochem 2009 (Lung Neoplasms) : The aim of this study was to investigate the synergistic induction of COX-2 by Ang II and pro-inflammatory cytokines in lung fibroblasts
Renno et al., Cell Mol Neurobiol 2012 (Diabetes Mellitus, Experimental) : We examined the effect of Ang- ( 1-7 ) on the number of cyclooxygenase-2 (COX-2) immunoreactive neurons and the glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes and assessed the changes in the neuronal growth associated protein-43 (GAP-43) of the hippocampal formation in streptozotocin induced diabetes in rats