Gene interactions and pathways from curated databases and text-mining

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PRKACB — SRF

Text-mined interactions from Literome

Nguyen et al., Cell Signal 2004 (Carcinoma, Hepatocellular...) : Treatment of OVCAR-3 cells with the F-actin stabilizing compound, jasplakinolide, prevented the protein kinase A (PKA) mediated inhibition of SRF ... These results suggest that PKA inhibits LPA stimulation of SRF by promoting the dissolution of F-actin and that this is likely to contribute to the cAMP mediated inhibition of ovarian cancer cell growth
Blaker et al., Arterioscler Thromb Vasc Biol 2009 : PKA dependent phosphorylation of serum response factor inhibits smooth muscle-specific gene expression