Gene interactions and pathways from curated databases and text-mining

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LIMK2 — RHOA

Text-mined interactions from Literome

Sumi et al., J Biol Chem 2001 : Activation of LIMK2 by RhoA was inhibited by Y-27632, a specific inhibitor of ROCK, but Rac1 mediated activation of LIMK1 was not
Geneste et al., J Cell Biol 2002 : Activation of SRF by overexpression of wild-type LIMK or ROCK-insensitive LIMK mutants also requires functional RhoA , indicating that a second RhoA dependent signal is involved