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BMP2 — NTRK3

Text-mined interactions from Literome

Jin et al., Cancer Res 2007 (Adenocarcinoma...) : In the highly metastatic CT26 murine colon cancer cell line, which expresses endogenous TrkC, silencing TrkC expression by small interfering RNA significantly enhanced BMP-2 induced Smad1 phosphorylation and restored BMP-2 growth inhibitory activity ... In contrast, expression of TrkC in RIE-1 cells, in which TrkC is not expressed, completely suppressed BMP-2 transcriptional activation ... Our findings provide evidence for a previously unknown mechanism by which TrkC , a neuronal receptor, can block BMP tumor-suppressor activity
Kobayashi et al., Brain Res Mol Brain Res 1998 : Induction of the functional TrkC receptor by BMP2 was confirmed by the enhancement of the survival response of these neurons to NT3