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BMP2 — MYOG
Text-mined interactions from Literome
Hewitt et al., Endocrinology 2008
:
BMP-2 suppressed the muscle transcription factor
myogenin , but expression of MyoD and Myf5 persisted
Murray et al., J Cell Biochem 1993
:
To gain insights into the mechanisms of action of BMP, we have studied the
effects of
BMP on the levels of expression of the four known myogenic determination genes
: myogenin , Myo D, herculin, and myf-5
Katagiri et al., Exp Cell Res 1997
:
Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by
suppressing the transcriptional activity of MyoD and
myogenin ... In the electrophoresis mobility shift assay using nuclear extracts of the myogenic cells, MyoD and
myogenin bound to the right E-box in the enhancer region of the MCK gene even in the
presence of
BMP-2
Namiki et al., J Biol Chem 1997
:
BMP-2 did not efficiently
suppress the mRNA expression of muscle-specific genes such as muscle creatine kinase, MyoD, and
myogenin , nor did it induce the expression of ALP mRNA in the DeltaBMPR-IA transfected C2C12 cells