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CRH — PRKACB
Text-mined interactions from Literome
Yamamori et al., J Mol Endocrinol 2004
(Calcium Signaling) :
Altogether, we conclude that not only the
cAMP/PKA but also the calcium/CaMKIV signaling pathway is
involved in the regulation of
CRH gene expression ... Furthermore, CREB is thought to be involved in CaMK- as well as
cAMP/PKA mediated
CRH gene expression
Agarwal et al., Brain Res Mol Brain Res 2005
:
Pituitary adenylate cyclase activating polypeptide ( PACAP ) mimics neuroendocrine and behavioral manifestations of stress : Evidence for
PKA mediated expression of the
corticotropin releasing hormone (CRH) gene
Nanmoku et al., Neurosci Lett 2005
(Second Messenger Systems) :
Furthermore, urocortin induced changes in TH-mRNA and activity were inhibited by H89 ( a
PKA inhibitor ) and SQ22536 as well as alpha-helical
CRF- ( 9-41 )
Hu et al., J Endocrinol 1992
(Second Messenger Systems) :
These data provide direct evidence for a
role for both PKC- and
PKA mediated mechanisms in the regulation of
CRF , AVP and oxytocin release and for differential effects of both glucocorticoids and mineralocorticoids on PKA- and PKC stimulated responses
Uh et al., Reproductive biology and endocrinology : RB&E 2009
:
Classically
protein kinase A (PKA) and transcription factor activator protein 1 (AP-1)
mediate the cyclic AMP ( cAMP )
induced-corticotrophin releasing hormone (CRH) expression in the placenta
Yang et al., Br J Pharmacol 2011
(Arrhythmias, Cardiac) :
Urocortin 2 enhanced contractility in mouse ventricular myocytes via activation of
CRF2 receptors in a
cAMP/PKA- and Ca² ( + ) /CaMKII
dependent manner
Ji et al., Molecular pain 2013
(Pain...) :
CRF increased a latent NMDA receptor mediated EPSC, and this effect also
required CRF1 and
PKA but not CRF2 and PKC
Gwosdow et al., Am J Physiol 1994
:
In contrast,
CRF stimulated
PKA activity and ACTH secretion were inhibited by 2'5'-DDA ... Inhibition of
PKA with the PKA inhibitor, H-8,
blocked activation of PKA and ACTH secretion by both IL-1 alpha and
CRF in AtT-20 cells