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IL3 — VAV1

Text-mined interactions from Literome

Machide et al., Oncogene 1995 : Interleukin 3 and erythropoietin induce association of Vav with Tec kinase through Tec homology domain ... In vitro binding assays showed that erythropoietin and IL3 stimulation induce the specific binding of Vav to Tec kinase through Tec homology domains
Hanazono et al., Acta Haematol 1996 : Here we report that granulocyte/macrophage-colony- stimulating factor ( GM-CSF ), interleukin-3 , and erythropoietin (Epo) induce rapid and transient tyrosine phosphorylation of Vav and that Vav is constitutively associated with the SH3 domain of Grb2/Ash in a human leukemia cell line UT-7 ... Here we report that granulocyte/macrophage-colony- stimulating factor ( GM-CSF ), interleukin-3 , and erythropoietin (Epo) induce rapid and transient tyrosine phosphorylation of Vav and that Vav is constitutively associated with the SH3 domain of Grb2/Ash in a human leukemia cell line UT-7
Fischer et al., Curr Biol 1998 : Vav is a crucial regulator of TCR mediated Ca2+ flux, cytoskeletal reorganization and TCR clustering, and these are required for T-cell maturation, interleukin-2 production and cell cycle progression