Gene interactions and pathways from curated databases and text-mining

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PKP4 — RHOA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: PKP4 — RHOA (interaction, mapped from grid kegg_pathways)
  • STRING interaction: RHOA — PKP4 (interaction, mapped from grid kegg_pathways)

Text-mined interactions from Literome

Keil et al., Cell cycle (Georgetown, Tex.) 2007 : Whereas p120(ctn) has a major function in regulating cell adhesion and motility through controlling Rho-GTPases, a recent report shows that the closely related protein p0071 associates and regulates RhoA at the cleavage furrow during cytokinesis ... Full activation of RhoA required Ect2 as well as p0071 indicating that these two proteins act in conjunction to regulate RhoA during cytokinesis
Keil et al., J Cell Sci 2009 : Additionally, p0071 plays a role in cytokinesis, in which it regulates local activation of RhoA together with Ect2