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PKP4 — RHOA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
STRING interaction:
PKP4
—
RHOA
(interaction, mapped from grid kegg_pathways)
-
STRING interaction:
RHOA
—
PKP4
(interaction, mapped from grid kegg_pathways)
Text-mined interactions from Literome
Keil et al., Cell cycle (Georgetown, Tex.) 2007
:
Whereas p120(ctn) has a major function in regulating cell adhesion and motility through controlling Rho-GTPases, a recent report shows that the closely related protein
p0071 associates and
regulates RhoA at the cleavage furrow during cytokinesis ... Full activation of
RhoA required Ect2 as well as
p0071 indicating that these two proteins act in conjunction to regulate RhoA during cytokinesis
Keil et al., J Cell Sci 2009
:
Additionally,
p0071 plays a role in cytokinesis, in which it
regulates local activation of
RhoA together with Ect2