Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — PARP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Idogawa et al., Gastroenterology 2005 (Cell Transformation, Neoplastic...) : PARP-1 physically interacted with TCF-4 and augmented the transcriptional activity of the beta-catenin/TCF-4 complex
Idogawa et al., Cancer Res 2007 : Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4 mediated gene transactivation : possible linkage of DNA damage recognition and Wnt signaling
Goto et al., Clin Cancer Res 2010 (Carcinoma, Squamous Cell...) : Rap1 stabilizes beta-catenin and enhances beta-catenin dependent transcription and invasion in squamous cell carcinoma of the head and neck ... Immunofluorescence studies showed that ectopic expression of Rap1 increased nuclear translocation of beta-catenin ... The findings suggest that Rap1 enhances beta-catenin stability and nuclear localization