Gene interactions and pathways from curated databases and text-mining

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CD8A — CSF2

Text-mined interactions from Literome

Ramsburg et al., J Virol 2005 : The primary CD8 T-cell and neutralizing antibody responses to VSV-GMCSF1 were equivalent to those generated by VSV-EGFP1, while the CD8 T-cell memory and recall responses to the vector were enhanced in mice infected with VSV-GMCSF1
Tenbusch et al., BMC immunology 2008 : To explore whether the targeting of antigens to GM-CSF receptors on antigen presenting cells enhances antigen-specific CD8 T-cell responses, fusion proteins of GM-CSF and ovalbumin ( OVA ) were expressed by DNA and adenoviral vector vaccines
Ganesh et al., Int Immunol 2009 (Thyroiditis, Autoimmune) : GM-CSF induced CD11c+CD8a -- dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis
Wong et al., J Immunol 2009 : IL-12p70 production was produced predominantly by CD8alpha ( + ) DCs and plasmacytoid DCs, and mediated by CD8 T cell derived cytokines IFN-gamma, GM-CSF , TNF-alpha, and surface CD40L
Yuan et al., Eur J Cancer Prev 2009 (Breast Neoplasms) : We also found that CD4 positive and CD8 positive lymphocytes were detected only in tumors grown in rBCG-MVNTR4/8-CSF immunized animals, and strong IFN-gamma responses were induced by immunization with rBCG-MVNTR4-CSF and rBCG-MVNTR8-CSF vaccines
Slingluff et al., Clin Cancer Res 2009 (Melanoma) : Effect of granulocyte/macrophage colony stimulating factor on circulating CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine : outcome of a multicenter randomized trial
Zhan et al., Eur J Immunol 2011 (Listeriosis) : This previously unrecognized functional enhancement of CD8 ( + ) DCs by GM-CSF was independent of promoting DC survival in vitro
Wanjalla et al., Virology 2012 (HIV Infections...) : A role for granulocyte-macrophage colony stimulating factor in the regulation of CD8 ( + ) T cell responses to rabies virus ... These data define a role of GM-CSF expression, in the regulation of the CD8 ( + ) T cell immune responses against RABV and has implications in the use of GM-CSF as a molecular adjuvant in vaccine development
Zhu et al., PloS one 2012 : GM-CSF increased monocyte derived DCs in mice and from mouse bone marrow cultured in vitro, but it did not increase CD8 ( + ) lymphoid derived DCs or B220 ( + ) plasmacytoid DCs ... GM-CSF increased the 5.3 Kb CD11c proximal promoter activity in monocyte derived DCs and CD8 ( + ) lymphoid derived DCs, but not in B220 ( + ) plasmacytoid DCs