◀ Back to CD8A
CD8A — CSF2
Text-mined interactions from Literome
Ramsburg et al., J Virol 2005
:
The primary
CD8 T-cell and neutralizing antibody
responses to
VSV-GMCSF1 were equivalent to those generated by VSV-EGFP1, while the CD8 T-cell memory and recall responses to the vector were enhanced in mice infected with VSV-GMCSF1
Tenbusch et al., BMC immunology 2008
:
To explore whether the targeting of antigens to
GM-CSF receptors on antigen presenting cells
enhances antigen-specific
CD8 T-cell responses, fusion proteins of GM-CSF and ovalbumin ( OVA ) were expressed by DNA and adenoviral vector vaccines
Ganesh et al., Int Immunol 2009
(Thyroiditis, Autoimmune) :
GM-CSF induced
CD11c+CD8a -- dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis
Wong et al., J Immunol 2009
:
IL-12p70 production was produced predominantly by
CD8alpha ( + ) DCs and plasmacytoid DCs, and
mediated by CD8 T cell derived cytokines IFN-gamma,
GM-CSF , TNF-alpha, and surface CD40L
Yuan et al., Eur J Cancer Prev 2009
(Breast Neoplasms) :
We also found that CD4 positive and
CD8 positive lymphocytes were detected only in tumors grown in rBCG-MVNTR4/8-CSF immunized animals, and strong IFN-gamma responses were
induced by immunization with
rBCG-MVNTR4-CSF and rBCG-MVNTR8-CSF vaccines
Slingluff et al., Clin Cancer Res 2009
(Melanoma) :
Effect of granulocyte/macrophage
colony stimulating factor on circulating
CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine : outcome of a multicenter randomized trial
Zhan et al., Eur J Immunol 2011
(Listeriosis) :
This previously unrecognized functional
enhancement of
CD8 ( + ) DCs by
GM-CSF was independent of promoting DC survival in vitro
Wanjalla et al., Virology 2012
(HIV Infections...) :
A
role for granulocyte-macrophage
colony stimulating factor in the regulation of
CD8 ( + ) T cell responses to rabies virus ... These data define a
role of
GM-CSF expression, in the regulation of the
CD8 ( + ) T cell immune responses against RABV and has implications in the use of GM-CSF as a molecular adjuvant in vaccine development
Zhu et al., PloS one 2012
:
GM-CSF increased monocyte derived DCs in mice and from mouse bone marrow cultured in vitro, but it did not
increase CD8 ( + ) lymphoid derived DCs or B220 ( + ) plasmacytoid DCs ...
GM-CSF increased the 5.3 Kb CD11c proximal promoter activity in monocyte derived DCs and
CD8 ( + ) lymphoid derived DCs, but not in B220 ( + ) plasmacytoid DCs