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ATP8A2 — TNF
Text-mined interactions from Literome
Boneberg et al., J Pharmacol Exp Ther 2001
:
Recombinant
ML-1 , but not the recombinant B-chain alone, also
increased TNF-alpha release and decreased IL-10 release
Nedrebø et al., J Physiol 2004
(Endotoxemia...) :
During endotoxaemia,
TNF-alpha increased in the IF from 0 in control to 640 +/- 100 pg
ml(-1) ( mean +/-s.e.m. ) after 90 min, with the serum concentration being 5-10 times higher at all time points
Komura et al., Journal of thrombosis and haemostasis : JTH 2008
:
Although 2 U
mL(-1) AT slightly
inhibited TNF-alpha production by LPS stimulated monocytes, it significantly inhibited TNF-alpha production in the presence of a low concentration of beraprost, a stable derivative of prostacyclin
Hostanska et al., Nat Immun 1995
:
Regarding cytokine secretion, IL-6 and
TNF-alpha production was
induced by 10 ng/ml
ML-I