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IGF2 — NOS3

Text-mined interactions from Literome

Sun et al., Zhonghua Kou Qiang Yi Xue Za Zhi 2004 : [ Effects of insulin-like growth factor II on regulating nitric oxide synthase gene expression in mouse osteoblast-like MC3T3-E1 cells ] ... To study the effects of insulin-like growth factor II (IGF-II) on regulating the levels of nitric oxide ( NO ) and the mRNA transcriptions of inducible nitric oxide synthase (iNOS) and endothelial NOS (eNOS) in mouse osteoblast-like cells
Sun et al., J Zhejiang Univ Sci B 2005 : Effects of IGF-II on promoting proliferation and regulating nitric oxide synthase gene expression in mouse osteoblast-like cell
Sukhanov et al., Arterioscler Thromb Vasc Biol 2007 (Atherosclerosis...) : Furthermore, IGF-1 decreased vascular expression of the proinflammatory cytokines interleukin-6 and tumor necrosis factor-alpha, reduced aortic superoxide formation and urinary 8-isoprostane levels, and increased aortic pAkt and eNOS expression and circulating endothelial progenitor cells, consistent with an antiinflammatory, antioxidant, and prorepair effect on the vasculature
Stone et al., J Gerontol A Biol Sci Med Sci 2012 : Moreover, IGF-1 also activated endothelial nitric oxide synthase in human umbilical vein endothelial cells