Gene interactions and pathways from curated databases and text-mining

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MYLIP — SMAD4

Text-mined interactions from Literome

Wang et al., Oncogene 2010 (Carcinoma, Hepatocellular...) : The levels of the precursor and mature miR-181b were augmented on exposure of hepatic cells to TGFbeta and were significantly reduced by small interference RNA mediated depletion of Smad4 , showing the involvement of TGFbeta signaling pathway in miR-181b expression
Long et al., J Biol Chem 2011 : siRNA studies demonstrated that the effect of TGF-ß1 on miR143/145 was dependent upon the myocardin and serum response factor transcriptional switch as well as SMAD4
Vaporidi et al., Am J Physiol Lung Cell Mol Physiol 2012 (Disease Models, Animal...) : In TGF-ß signaling network, SMAD-4 , regulated by miR-146 , appeared as a central node
Dey et al., Genes Dev 2012 : Inhibiting miR-26a in the tibialis anterior muscles through the injection of adeno associated virus expressing a Tough-Decoy targeting miR-26a prevents Smad down-regulation and delays regeneration
Liang et al., Mol Cell Endocrinol 2013 : We previously reported that miR-224 is involved in TGF-ß1 mediated follicular granulosa cell ( GC ) growth and estradiol ( E2 ) production by targeting Smad4
Lu et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2013 : [miR-125b regulates osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting Smad4 ]