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FGFR2 — MYLIP

Text-mined interactions from Literome

Rio-Machin et al., Leukemia 2013 (Multiple Myeloma...) : We found that target genes of the most differentially expressed miRNAs are directly involved in the pathogenesis of MM ; specifically, the inhibition of hsa-miR-425 , hsa-miR-152 and hsa-miR-24, which are all downregulated in h-MM, leads to the overexpression of CCND1, TACC3, MAFB, FGFR3 and MYC, which are the also the oncogenes upregulated by the most frequent IgH chromosomal translocations occurring in nh-MM. Importantly, we showed that the downregulation of these specific miRNAs and the upregulation of their targets also occur simultaneously in primary cases of h-MM
Mor et al., Neurobiol Dis 2013 (Postmortem Changes) : We further found that miR-382 directly regulates the expression of two genes, FGFR1 and SPRY4, which are downregulated in both the cultured olfactory cells and LCM-OE derived from schizophrenia patients