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MMP1 — SPP1

Text-mined interactions from Literome

Bendeck et al., Arterioscler Thromb Vasc Biol 2000 (Carotid Artery Injuries) : Stimulation of newborn ( alpha ( v ) beta ( 3 ) + ) SMCs with osteopontin , a matrix ligand for alpha ( v ) beta ( 3 ), increased MMP-1 production from 114.4+/-35.8 ng/mL at 0 nmol/L osteopontin to 232.5+/-57.5 ng/mL at 100 nmol/L osteopontin
Pardo et al., PLoS Med 2005 (Pulmonary Fibrosis) : In fibroblasts, osteopontin up-regulated tissue inhibitor of metalloprotease-1 and type I collagen, and down-regulated matrix metalloprotease-1 (MMP-1) expression, while in A549 cells it caused up-regulation of MMP-7
Lai et al., Circ Res 2006 : To better understand its role in vascular remodeling, we assessed how OPN controls metalloproteinase ( MMP ) activation in aortic adventitial myofibroblasts ( AMFs ) and A7r5 vascular smooth muscle cells ( VSMCs )
Hayami et al., Matrix Biol 2008 : Overexpression of MMP-1 resulted in a significant decrease in Runx2, osteonectin (ON), osteopontin (OP) , bone sialoprotein ( BSP ) and osteocalcin ( OC ), but an increase in osterix ( Osx ) mRNA levels
Castellano et al., Clin Cancer Res 2008 (Disease Progression...) : Osteopontin (OPN) , which activates matrix metalloproteinases ( MMP ) , is considered a prognostic biomarker in several cancers ... `` In silico '' and experimental approaches were used to determine whether OPN mediated MMP activation may be a signal of prostate cancer progression
Suzuki et al., Crit Care Med 2010 (Brain Injuries...) : Body weight, neurologic scores, brain edema, and blood-brain barrier disruption were evaluated, and Western blot analyses were performed to determine the effect of recombinant osteopontin on matrix metalloproteinase-9, substrates of matrix metalloproteinase-9 ( zona occludens-1, laminin ), tissue inhibitor of matrix metalloproteinase-1 , inflammation ( interleukin-1beta ), and nuclear factor-kappaB signaling pathways
Buommino et al., Arch Dermatol Res 2012 (Psoriasis) : Interestingly, MMP-9 expression can be enhanced also by osteopontin (OPN) , a glycosylated protein whose levels are increased in skin and peripheral blood mononuclear cells ( PBMC ) of psoriasis patients
Tan et al., Lab Invest 2013 (Fibrosis...) : Moreover, MMP-9 inhibition caused a significant reduction in MMP-9 cleaved osteopontin and macrophage infiltration in UUO kidney