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NODAL — POU5F1
Text-mined interactions from Literome
He et al., Stem Cells 2009
:
Nodal activates Smad2/3 phosphorylation,
Oct-4 transcription, cyclin D1, and cyclin E expression, whereas SB431542 completely abolishes their increase
Wu et al., Biol Reprod 2010
:
Additionally, expression of
NODAL , a putative autocrine
regulator of
POU5F1 expression in mouse germ cells, could not be detected in SSCs isolated from testes or cultured SSCs. Collectively, these results indicate that POU3F1, but not POU5F1, is an intrinsic regulator of GDNF induced survival and self-renewal of mouse SSCs