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JUN — PTPN11

Text-mined interactions from Literome

Lerner-Marmarosh et al., Arterioscler Thromb Vasc Biol 2003 (Inflammation) : TNF-alpha mediated JNK, c-Jun , and NF-kappaB activation required Src and SHP-2 activity ... A catalytically inactive form of SHP-2 increased MEKK3/Gab1 interaction and inhibited MEKK3 ( but not MEKK1 ) -mediated c-Jun and NF-kappaB activation
Bakken et al., Virology 2010 : We find that vGPCR activity results in phosphorylation of regulatory tyrosines in Shp2 and that in turn, Shp2 is required for vGPCR mediated activation of MEK, NFkappaB, and AP-1
Deb et al., J Biol Chem 1998 : A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation