Gene interactions and pathways from curated databases and text-mining

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KDR — PTN

Text-mined interactions from Literome

Sharifi et al., Arterioscler Thromb Vasc Biol 2006 (Ischemia) : RT-PCR, real-time PCR, and fluorescence activated cell sorter analysis revealed that the expression of PTN by monocytic cells led to a downregulation of CD68, c-fms, and CD14 monocytic cell markers and an upregulation of FLK-1 , Tie-2, vascular endothelial-cadherin, platelet endothelial cell adhesion molecule-1, endothelial NO synthase, von Willebrand factor, CD34, GATA-2, and GATA-3 endothelial cell markers
Dineen et al., Cancer Res 2008 (Pancreatic Neoplasms) : Additionally, we found that the cytokine pleiotrophin is sufficient to induce VEGFR2 expression on macrophages