◀ Back to NFKB1

NFKB1 — ROCK2

Text-mined interactions from Literome

Wei et al., Mol Pharmacol 2006 : Further studies showed that LPS down-regulated Rho and ROCK activity, whereas IL-1beta increased them, suggesting a negative role of Rho and ROCK signaling, which is regulated in contrary manners by IL-1beta and LPS, in IKK/NF-kappaB activation
Rodriguez et al., Cell Signal 2007 : Thus, ROCK I cooperates with RhoB to activate NF-kappaB, and suppression of ROCK I activity by genetic or pharmacological inhibitors blocks NF-kappaB activation
Mattaliano et al., Am J Physiol Cell Physiol 2010 : In addition, OxLDL treatment stimulated ROCK2 catalytic activity, and ROCK2 inhibition attenuated NF-kappaB activation and IL-8 production resulting from OxLDL activation of LOX-1
Shimada et al., FEBS Lett 2010 : In summary, MCP-1 production was partly regulated by ROCK acting upstream of p38 and JNK and mediated downstream by NF-kappaB