Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
MEF2C
→
CDK4
(decreases, CDK4 Activity, MEF2C Activity)
Lazaro et al., Genes Dev 2002* Evidence: Our findings indicate that cyclin D-cdk4 activity represses skeletal muscle differentiation in proliferating cells by blocking the association of MEF2 with the coactivator GRIP-1 and concomitantly disrupts the association of these factors with punctate nuclear subdomains within the cell.