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MAP3K1 — NOS2

Text-mined interactions from Literome

Pawate et al., Antioxid Redox Signal 2006 : While an inhibitor of the JNK pathway ( SP600125 ) inhibited iNOS expression, ectopic expression of a constitutively active form of MEKK1 ( MAPK/ERK kinase kinase- 1 ), an upstream activator of JNK, led to an induction of co-transfected iNOS promoter activity and, in the presence of LPS, to an enhanced expression of iNOS
Mokhtari et al., Diabetes 2008 : MEKK-1 mediates cytokine induced JNK- and NF-kappaB activation, and this event is necessary for iNOS expression and cell death