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ITGB2 — NFKB1

Pathways - manually collected, often from reviews:

• NCI Pathway Database amb2 Integrin signaling: alphaM/beta2 Integrin/RAGE/HMGB1 complex (ITGAM-ITGB2-AGER-HMGB1) → NF kappa B1 (NFKB1) (modification, activates) Pullerits et al., Arthritis Rheum 2006*, Orlova et al., EMBO J 2007
  Evidence: mutant phenotype, assay

Text-mined interactions from Literome

Wong et al., Am J Respir Cell Mol Biol 2003 : IL-3, IL-5, and GM-CSF could enhance p38 MAPK and NF-kappaB activity and induce ICAM-1, CD11b, and CD18 expressions on eosinophils
Lee et al., Immunol Lett 1996 : The NF-kappa B inhibitor, tepoxalin, suppresses surface expression of the cell adhesion molecules CD62E, CD11b/CD18 and CD106
Kurose et al., J Clin Invest 1997 : CD18/ICAM-1 dependent oxidative NF-kappaB activation leading to nitric oxide production in rat Kupffer cells cocultured with syngeneic hepatoma cells