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IL2 — TNFSF4

Text-mined interactions from Literome

Grosenbach et al., Cell Immunol 2003 : These studies demonstrate that ( a) OX40L plays a role in sustaining the long-term proliferation of CD8 ( + ) T cells in addition to the known effect on CD4 ( + ) T cells following activation, ( b ) OX40L enhances the production of Th1 cytokines ( IL-2 , IFN-gamma, and TNF-alpha ) from both CD4 ( + ) and CD8 ( + ) while no change in IL-4 expression was observed, and ( c ) the anti-apoptotic effect of OX40L on T cells is likely the result of sustained expression of anti-apoptotic genes while genes involved in apoptosis are inhibited
Lee et al., Immunology 2008 : We found that de novo expression or overexpression of OX40L , 4-1BBL and IL-12p70 on activated B cells synergistically enhanced proliferation as well as IL-2 and interferon-gamma production by CD8+ T cells
Walch et al., J Immunol 2009 : DCs infected with HSV-1 showed enhanced surface expression of the costimulatory molecule CD252 ( CD134L ) compared with Listeria infected DC and induced enhanced secretion of IL-2