◀ Back to IL2

IL2 — TGFB2

Text-mined interactions from Literome

Zhao et al., Cancer Immunol Immunother 2002 (Liver Neoplasms, Experimental) : We have previously reported that transforming growth factor beta ( TGF-beta ) produced by rat hepatoma cell line KDH-8 cells suppressed the interleukin-2 (IL-2) production of T cells and the tumoricidal activity of macrophages in KDH-8 tumor bearing rats and that the inhibition of TGF-beta production by low-dose bleomycin restored these activities significantly
Riemekasten et al., Arthritis Rheum 2003 : Interferon-gamma (IFNgamma), interleukin-2 (IL-2), IL-4, transforming growth factor beta , and IL-10 production increased in response to the peptide in young mice ; only IFNgamma and IL-2 were increased in older, diseased mice
Bry et al., Am J Obstet Gynecol 1992 (Obstetric Labor, Premature) : Human amnion cells in monolayer culture were treated with interleukin-1 , tumor necrosis factor, or vehicle in the presence or absence of transforming growth factor-beta
Brooks et al., Immunology 1992 : Recombinant human interleukin-4 (IL-4) and transforming growth factor-beta ( TGF-beta ) reduce recombinant interleukin-2 (IL-2) induction of lymphokine activated killer ( LAK ) cell activity from human peripheral blood mononuclear cells ( PBMC )
Layh-Schmitt et al., Curr Opin Rheumatol 2008 (Spondylarthropathies) : In mice, transforming growth factor-beta and interleukin-6 are critical, whereas interleukin-23 is more important at later stages promoting interleukin-17 production
Chakraborty et al., Clin Immunol Immunopathol 1991 : The suppression of high-affinity IL-2R induction on T cells did not result from tumor necrosis factor-alpha and beta or from transforming growth factor-beta as these cytokines were not detected in the cell-free supernatant from the MJ TIL culture
Espevik et al., Cell Immunol 1990 : The effect of recombinant ( r ) interleukin-1 beta ( rIL-1 beta ) and transforming growth factor-beta ( TGF-beta ) on the production of interleukin-2 (IL-2) and interleukin-6 (IL-6) from an antigen-specific ( LBRM-33-1A5 ) and an antigen-nonspecific ( EL-4-NOB-1 ) T-cell line was investigated
Ruegemer et al., J Immunol 1990 : Regulatory effects of transforming growth factor-beta on IL-2- and IL-4 dependent T cell-cycle progression
Kuppner et al., J Neurosurg 1989 (Brain Neoplasms...) : The results demonstrate that the IL-2 ( 5 to 20 U/ml ) -dependent proliferative response of glioma derived TIL 's was inhibited 70 % to 85 % by G-TsF/TGF beta 2 and that the inhibitory effect could be reduced by using increasing concentrations of IL-2 ( 100 to 200 U/ml )
Hoehn et al., J Immunol 1995 : In the presence of TGF-beta 2 , the production of IL-2 was completely suppressed if such T cells were activated solely by anti-CD3 mAb, but it was only partially inhibited after costimulation by anti-CD28 mAb ... Therefore, the opposing effect of TGF-beta 2 on the Th1 cell development of naive CD4+ T cells from different mouse strains appears to be the result of the variable potency of the respective CD4+ T cells to produce IL-2 in the presence of TGF-beta 2
Ye et al., J Leukoc Biol 1995 : Furthermore, both transforming growth factor-beta and genistein, a tyrosine kinase inhibitor, could suppress IL-2 and IL-12 signaling but CsA was generally inactive
Cardillo et al., Eur J Immunol 1993 (Autoimmune Diseases...) : This suppression could not be reverted by exogenous interleukin (IL)-2 and was not directly dependent on the presence of IL-4, IL-10 or transforming growth factor-beta
Marth et al., Eur J Immunol 1997 : Regulation of transforming growth factor-beta production by interleukin-12
Fulton et al., J Infect Dis 1998 : Regulation of interleukin-12 by interleukin-10, transforming growth factor-beta , tumor necrosis factor-alpha, and interferon-gamma in human monocytes infected with Mycobacterium tuberculosis H37Ra