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STAT6 — TYK2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Nath et al., J Immunol 2004
(Encephalomyelitis, Autoimmune, Experimental...) :
Lovastatin
induced the expression of GATA3 and the phosphorylation of
STAT6 , whereas it inhibited tyrosine phosphorylation of Janus kinase 2,
tyrosine kinase 2 , and STAT4
Wan et al., J Cell Mol Med 2008
(Carcinoma, Hepatocellular...) :
The activation of
STAT6 by type I IFN in hepatocytes was
mediated by JAK1 and
Tyk2
Zhang et al., FASEB J 2012
(Hyperplasia...) :
Mechanistically, Gab2 positively
regulates IL-13 induced activation of
TYK2/STAT6 by decreasing SOCS3 mediated degradation of
TYK2
Bhattacharjee et al., Free Radic Biol Med 2013
:
We further show that Jak2 is upstream of Stat3 activation and
Tyk2 controls Stat1 and
Stat6 activation in response to IL-13 stimulation