Gene interactions and pathways from curated databases and text-mining

◀ Back to IFNG

IFNG — TNFRSF9

Text-mined interactions from Literome

Sun et al., J Immunol 2006 (Bronchial Hyperreactivity...) : The engagement of CD137 ( 4-1BB ), an inducible T cell costimulatory receptor and member of the TNF receptor superfamily, by agonistic Abs can promote strong tumor and viral immunity mediated by CD8 ( + ) T cells and stimulate IFN-gamma production
Wang et al., Croat Med J 2008 (Carcinoma...) : Furthermore, CD137L expression found on tumor cell lines was functional because the ligation of CD137L on lung squamous carcinoma cells L78 with CD137 on T cells induced IFN-gamma production by T cells, and ligation of CD137L on hepatocarcinoma cells HepG2.2.15 with CD137 triggered tumor cells to produce IL-8
Zhang et al., J Immunol 2010 : In vitro CD137 expression is enhanced by CD40 stimulation and IFN-gamma and is inhibited by IL-4, -10, and -21