Gene interactions and pathways from curated databases and text-mining

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IFNG — IL4R

Text-mined interactions from Literome

So et al., J Immunol 2000 : In human mononuclear cells and B cells isolated from tonsil or peripheral blood, IL-4 up-regulates IL-4R(alpha) expression at surface protein and mRNA levels, and the IL-4 induced IL-4R(alpha) is significantly down-regulated by both IFN-gamma and IFN-alpha to a similar extent
Strait et al., J Immunol 2003 (Anaphylaxis...) : This effect was inhibited by endogenously produced IFN-gamma , was T cell-, B cell-, and common gamma-chain independent, and required IL-4Ralpha and Stat6
Yamamoto et al., Am J Respir Cell Mol Biol 2004 : Upregulation of interleukin-4 receptor by interferon-gamma : enhanced interleukin-4 induced eotaxin-3 production in airway epithelium ... IFN-gamma also increased the mRNA expression and protein production of IL-4 receptor (R) alpha in a time- and dose dependent manner