Gene interactions and pathways from curated databases and text-mining

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PTEN — SRC

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Lu et al., J Biol Chem 2003 (Breast Neoplasms) : Further, expression of activated Src results in marked tyrosine phosphorylation of PTEN
Kim et al., Eur J Pharmacol 2011 (Multiple Myeloma) : Icariside II inhibited STAT3 activation and enhanced the expression of SHP-1 and PTEN through inhibiting Janus activated kinase 2 (JAK2) and c-Src