Gene interactions and pathways from curated databases and text-mining

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IL10 — LTF

Text-mined interactions from Literome

Togawa et al., Am J Physiol Gastrointest Liver Physiol 2002 (Colitis) : Lactoferrin caused significant induction of the anti-inflammatory cytokines interleukin (IL)-4 and IL-10 , significant reductions in the proinflammatory cytokines tumor necrosis factor-alpha and IL-1beta, and downregulation of the nuclear factor-kappaB pathway
Hwang et al., Med Microbiol Immunol 2007 : In all scenarios tested, Lactoferrin induced a strong increase in the ratio of IL-12 : IL-10 production from LPS stimulated cells
Adamik et al., Arch Immunol Ther Exp (Warsz) 1998 (Critical Illness...) : We studied the effect of lactoferrin (LF) on the proliferative response of peripheral blood mononuclear cells ( PBMC ) to lipopolisaccharide (LPS) in vitro and its influence on production of 2 proinflammatory cytokines : interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha)