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APOE — SDC2
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
APOE
→
SDC2
(direct_complex)
Futamura et al., J Biol Chem 2005, Yamauchi et al., Biochemistry 2008, Ji et al., J Biol Chem 1993
-
Reactome Reaction:
APOE
→
SDC2
(reaction)
Futamura et al., J Biol Chem 2005, Yamauchi et al., Biochemistry 2008, Gad et al., J Lipid Res 1991, Harrison et al., J Biol Chem 1989, Hagen et al., J Lipid Res 1999
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
de Beer et al., Arterioscler Thromb Vasc Biol 1999
(Arteriosclerosis) :
In the present study we investigated the effect of the isoform and the amount of
apoE per particle, as well as the
role of LPL on the binding of beta-VLDL to
HSPG
Chen et al., Proc Natl Acad Sci U S A 2011
:
Binding to lipid and
heparan sulfate proteoglycans (HSPG) induces
apoE to adopt active conformations for binding to low-density lipoprotein receptor (LDLR) family
van Barlingen et al., J Lipid Res 1996
:
Both LPL and
apoE increased the ability of TRLP to bind
HSPG