Gene interactions and pathways from curated databases and text-mining

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EPHB2 — NFATC1

Text-mined interactions from Literome

Chen et al., J Exp Med 2003 : We show that in stimulated CD4+ T cells, TGF-beta inhibits phosphorylation and activation of the Tec kinase Itk, increase in intracellular Ca2+ levels, NFATc translocation, and activation of the mitogen activated protein kinase ERK that together regulate T cell differentiation
Park et al., Biochem Pharmacol 2008 (Bone Resorption) : In conclusion, bavachalcone inhibits osteoclastogenesis by interfering with the ERK and Akt signaling pathways and the induction of c-Fos and NFATc1 during differentiation
Kalliolias et al., Arthritis Rheum 2010 (Arthritis, Rheumatoid...) : IL-27 inhibited human osteoclastogenesis, suppressed the induction of NFATc1 , down-regulated the expression of RANK and triggering receptor expressed on myeloid cells 2 ( TREM-2 ), and inhibited RANKL mediated activation of ERK , p38, and NF-kappaB in osteoclast precursors