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CAPN2 — PARP1

Text-mined interactions from Literome

Sohn et al., Cancer Lett 2003 (Carcinoma, Hepatocellular...) : TG-induced apoptosis was assessed by morphological changes, DNA fragmentation, cleavages of poly ( ADP-ribose ) polymerase ( PARP ), and activation of calpain and caspase-12
Vosler et al., Exp Neurol 2009 : Both calpain and PARP-1 are involved with AIF processing as AIF truncation, nuclear translocation and neuronal death were attenuated by calpain inhibition using adeno associated virus mediated overexpression of the endogenous calpain inhibitor, calpastatin, or treatment with the PARP-1 inhibitor 3-ABA ... Activation of PARP-1 is necessary for calpain activation as PARP-1 inhibition blocked mitochondrial calpain activation