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EPHB2 — PF4
Text-mined interactions from Literome
Sulpice et al., Blood 2002
(MAP Kinase Signaling System) :
To exclude the possibility that PF-4 inhibited the binding of FGF2 to only one FGF receptor, preferentially activating the ERK pathway, we investigated the
effect of
PF-4 on FGF2 induced
ERK and Akt phosphorylation, using mutant heparan sulfate-deficient Chinese hamster ovary cells transfected with the FGF-R1 cDNA
Kasper et al., J Immunol 2007
:
However,
PF4 induced up-regulation of chemokine and cytokine mRNA and protein
requires a sustained activation of JNK and
Erk
Nawaz et al., Exp Eye Res 2013
(Diabetic Retinopathy...) :
On the other hand, phosphorylation of
ERK induced by VEGF and MCP-1 was
inhibited by
PF-4 , Mig and IP-10