◀ Back to SRC
PRKCA — SRC
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Gatesman et al., Mol Cell Biol 2004
:
We report that the actin filament associated protein AFAP-110 is required to mediate
protein kinase Calpha (PKCalpha) activation of the nonreceptor tyrosine kinase
c-Src and the subsequent formation of podosomes ... Ectopic expression of AFAP-110 in CaOV3 cells rescued
PKCalpha mediated activation of
c-Src and elevated tyrosine phosphorylation levels and subsequent formation of podosomes
Pula et al., J Biol Chem 2005
:
PKCalpha also associates with Src ; although in contrast to interaction with Syk,
PKCalpha activity is
required for the association of these kinases but not the stimulation induced translocation of
Src to the cell membrane
Cassese et al., J Biol Chem 2008
(Hyperglycemia) :
Here we show that HGA induced
PKCalpha activation is
mediated by
Src
Lee et al., J Cell Physiol 2010
(MAP Kinase Signaling System) :
Taken together, these data suggest that in A549 cells, TNF-alpha induces MMP-9 expression via the
TNFR1/TRAF2/PKCalpha dependent JNK1/2/c-Jun and
c-Src/EGFR/PI3K/Akt pathways
Wali et al., Biochem Biophys Res Commun 1998
:
Furthermore, 1,25-dihydroxyvitamin D3 specifically induced the translocation of PKC-betaII, but not
PKC-alpha , to the basolateral, but not brush-border plasma membranes of rat colonocytes, via a
pp60(c-src) dependent mechanism