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Alhan et al., Eur Surg Res 2006 (Pancreatitis, Acute Necrotizing) : The induction of ANP resulted in a significant increase in mortality rate, pancreatic necrosis, and serum levels of amylase, alanine aminotransferase, interleukin-6, tumor necrosis factor alpha, and urea, in lactate dehydrogenase levels in bronchoalveolar lavage fluid, and in the activities of myeloperoxidase and malondialdehyde in pancreas and lung tissue ; a significant decrease was observed in serum calcium levels, blood pressure, urine output, and pO ( 2 )
Alhan et al., Eur Surg Res 2006 (Pancreatitis, Acute Necrotizing) : The induction of ANP resulted in significant increases in mortality rate, intestinal permeability, bacterial infection in pancreas and extrapancreatic organs, and serum activity of urea and amylase, alanine transferase ( ALT ), interleukin (IL)-6, tumor necrotizing factor-alpha ( TNF-alpha ), lactate dehydrogenase ( LDH ) in bronchoalveolar lavage (BAL) fluid, tissue activity of myeloperoxidase (MPO) and malondialdehyde ( MDA ) in the pancreas and lung, and a considerable decrease of concentrations of calcium, protein and albumin
Nakayama et al., J Pharmacol Exp Ther 2007 (Reperfusion Injury...) : ANP inhibited I/R induced increases in spinal cord tissue levels of tumor necrosis factor and myeloperoxidase
Turkyilmaz et al., J Surg Res 2008 (Disease Models, Animal...) : ANP also increased levels of amylase and alanine aminotransferase ( ALT ) in serum, increased levels of urea and lactate dehydrogenase in bronchoalveolar lavage fluid ( BAL LDH ), increased the activities of myeloperoxidase (MPO) and malondialdehyde ( MDA ) in pancreas and lung tissue, and decreased the serum calcium levels