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IL10 — IL13

Text-mined interactions from Literome

Qiu et al., Zhongguo Yao Li Xue Bao 1999 : Inhibitory effects of nitric oxide and interleukin-10 on production of tumor necrosis factor alpha, interleukin-1 beta, and interleukin-6 in mouse alveolar macrophages
Pacocha et al., J Interferon Cytokine Res 2000 : Finally, whereas IFN-beta inhibited antigen-driven generation of IL-5, IL-12, IL-13 , and IFN-gamma, IFN-beta enhanced generation of both IL-4 and IL-10
Cohen et al., Eur Cytokine Netw 2000 : IL-13 could not be detected in any serum sample, whereas IL-10 could be detected in adult but not CB serum ( P < 0.002 )
Kelly et al., Reproduction 2001 : Prostaglandins have major effects on cytokine production but the direct action of prostaglandin E on leucocytes is not a pro-inflammatory response but is to stimulate interleukin 10 and inhibit interleukin 12 synthesis
Byrnes et al., Ann Neurol 2002 (Multiple Sclerosis, Chronic Progressive...) : Interleukin-10 , a dominant endogenous inhibitor of interleukin-12 , is largely protective in these experimental surrogates for multiple sclerosis
Puliti et al., Arthritis Rheum 2002 (Arthritis, Infectious...) : The beneficial effect of interleukin-12 on arthritis induced by group B streptococci is mediated by interferon-gamma and interleukin-10 production
Uchimura et al., Clin Exp Immunol 2002 (Graves Disease) : The effects of CD40- and interleukin ( IL-4 ) -activated CD23+ cells on the production of IL-10 by mononuclear cells in Graves ' disease : the role of CD8+ cells
Lutz et al., J Immunol 2002 : In contrast, the production of IL-12 p70, but not IL-10 and TNF, induced by microbial products was enhanced only by IL-4, not by IL-13 or Y119D, a selective type II IL-4R agonist, in vitro and in vivo
Cattaruzza et al., J Biol Chem 2003 : Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40 mediated interleukin-12 synthesis in human endothelial cells
Chiang et al., Am J Respir Crit Care Med 2003 (Asthma...) : The data showed that ribavirin and ODN 1826 increased interleukin-12 synthesis and inhibited interleukin-10 production
Jani et al., Plant Cell Rep 2004 : Macrophages isolated from mice immunised with native or plant expressed CTB showed enhanced secretion of interleukin-10 but secretion of lipopolysaccharide induced interleukin-12 and tumor necrosis factor alpha was inhibited
Weir et al., Infect Immun 2004 (Tuberculosis) : Mycobacterial purified protein derivatives stimulate innate immunity : Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom ... To investigate the role of innate immunity in variable efficacy of Mycobacterium bovis BCG vaccination in Malawi and the United Kingdom, we examined 24-h tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses to mycobacterial purified protein derivatives ( PPDs )
Zhou et al., Mol Cell Biol 2004 : Interleukin-10 inhibits interleukin-12 p40 gene transcription by targeting a late event in the activation pathway
Romano et al., Clin Immunol 2005 (Acute Disease...) : The role of interleukin-10 in the differential expression of interleukin-12p70 and its beta2 receptor on patients with active or treated paracoccidioidomycosis and healthy infected subjects
Melk et al., Transplantation 2004 (Growth Disorders...) : During rhGH therapy in children with transplants, interleukin (IL)-2 production increased threefold at 4 weeks, and IL-4 and IL-13 increased by 70 % at 12 weeks
Peek et al., Am J Respir Cell Mol Biol 2005 (Dermatitis, Atopic) : Allergen-specific T cell lines induced in the presence of salmeterol and fluticasone proprionate inhibited IL-5 and IL-13 production by allergen-specific Th2 cell lines in an IL-10 dependent manner
Mangan et al., J Immunol 2006 (Bronchial Hyperreactivity...) : Worm infected mice developed a novel modified type 2 cytokine response in the lungs, with elevated allergen-specific IL-4 and IL-13 but reduced IL-5, and increased IL-10
Obonyo et al., FEMS Immunol Med Microbiol 2006 (Helicobacter Infections) : Evidence for interleukin-1 independent stimulation of interleukin-12 and down-regulation by interleukin-10 in Helicobacter pylori infected murine dendritic cells deficient in the interleukin-1 receptor
Lukacs et al., Am J Pathol 2006 (Bronchial Hyperreactivity...) : When examining cytokine responses, A2 strain induced significant interleukin (IL)-10 expression, whereas Line 19 strain induced significant IL-13 expression
Forsythe et al., Am J Respir Crit Care Med 2007 (Asthma...) : Oral treatment with live Lactobacillus reuteri but not Lactobacillus salivarius significantly attenuated the influx of eosinophils to the airway lumen and parenchyma and reduced the levels of tumor necrosis factor, monocyte chemoattractant protein-1, IL-5, and IL-13 in bronchoalveolar lavage fluid of antigen challenged animals, but there was no change in eotaxin or IL-10
Mas et al., Mult Scler 2007 (Genetic Predisposition to Disease...) : OPN enhances the production of the pro-inflammatory cytokines, interleukin-12 and interferon-gamma, while reducing interleukin-10 levels
Yin et al., J Toxicol Environ Health 2007 (Listeriosis) : DEP or eDEP concentration-dependently suppressed L. monocytogenes induced secretion of tumor necrosis factor-alpha, interleukin (IL)-1beta , and IL-12 by AM and of IL-2 and interferon-gamma by lymphocytes obtained from L. monocytogenes infected rats, but augmented the AM secretion of IL-10
Edwan et al., Immunol Res 2007 (Asthma) : pUMVC3-hFLex treatment prevented the development of goblet cell hyperplasia and subepithelial fibrosis, and significantly reduced serum levels of IL-4 and IL-5, and increased serum IL-10 levels ( p < 0.05 ) with no effect on serum IL-13
Haber et al., Exp Parasitol 2009 (Hyperalgesia...) : Leishmania major : interleukin-13 increases the infection induced hyperalgesia and the levels of interleukin-1beta and interleukin-12 in rats
Buisson et al., J Infect Dis 2009 (HIV Infections) : These functional changes may be at least partly explained by reduced interleukin-12 and increased interleukin-10 secretion on stimulation with lipopolysaccharide and CD40 ligand
Elliott et al., Vaccine 2010 (HIV Infections...) : Maternal Mansonella perstans infection was associated with higher interleukin (IL)-10 responses to both immunogens but no reduction in gamma interferon ( IFN-? ), IL-5 and IL-13 responses ; other maternal helminth infections showed little effect
Mentink-Kane et al., Gastroenterology 2011 (Disease Models, Animal...) : IL-10 , IL-12p40, and IL-13Ra2 reduced the production and activity of the profibrotic cytokine IL-13
Ding et al., ACS Appl Mater Interfaces 2011 : The inhibition of inducible nitric oxide synthase and interleukin-1 expression and the activation of interleukin-10 were increased with increasing gelatin content
Newcomb et al., J Immunol 2012 (Pneumonia...) : IL-13 regulates Th17 secretion of IL-17A in an IL-10 dependent manner ... In this study, we extend our in vitro findings and determine that IL-13 increases IL-10 production from Th17 polarized cells and that IL-13 induced IL-10 production negatively regulates the secretion of IL-17A and IL-21 ... To determine if IL-13 negatively regulates lung IL-17A expression via an IL-10 dependent mechanism in vivo, we used a model of respiratory syncytial virus ( RSV ) strain A2 infection in STAT1 knockout ( KO ) mice that increases lung IL-17A and IL-13 expression, cytokines not produced during RSV infection in wild-type mice
Uchiyama et al., Journal of cardiothoracic surgery 2012 : Proliferation of splenocytes, interleukin (IL)-2 and interferon ( IFN ) -? production was suppressed in opera exposed mice, and production of IL-4 and IL-10 from opera exposed transplant recipients increased compared to that from splenocytes of untreated recipients
Daniłowicz-Luebert et al., Int J Parasitol 2013 (Hypersensitivity) : Ex vivo restimulation with cystatin of spleen cells from cystatin treated mice induced the production of IL-10 , while cystatin inhibited allergen-specific IL-5 and IL-13 levels
Chung et al., J Infect Dis 2013 (Leprosy, Lepromatous...) : Galectin-3 enhanced monocyte interleukin 10 production to a TLR2/1 ligand, whereas interleukin 12p40 secretion was unaffected
Haben et al., Eur J Immunol 2013 (Disease Models, Animal...) : Litomosoides sigmodontis-specific IFN-?, IL-5, and IL-13 production increased in the absence of T-cell derived IL-10 at early and late time points of infection
Sun et al., Clin Exp Immunol 2013 (Bronchial Hyperreactivity...) : We identified a subset of CD11b ( + ) CD11c ( + ) CD49b ( + ) F4/80 ( - ) Gr-1 ( - ) myeloid cells as a prinicipal source of IL-10 induced IL-13 production
Thompson et al., J Neurotrauma 2013 (Spinal Cord Injuries) : The best characterized effects of IL-10 are anti-inflammatory-it downregulates pro-inflammatory species interleukin-1ß (IL-1ß), interleukin-2 (IL-2), interleukin-6 (IL-6), tumor necrosis factor-a, interferon-?, matrix metalloproteinase-9, nitric oxide synthase, myeloperoxidase, and reactive oxygen species
de Waal Malefyt et al., J Immunol 1993 : However, IL-13 strongly inhibited spontaneous and IL-10- or IFN-gamma induced ADCC activity of human monocytes toward anti-D coated Rh+ erythrocytes, indicating that the cytotoxic activity of monocytes was inhibited ... Furthermore, IL-13 inhibited production of IL-1 alpha, IL-1 beta, IL-6, IL-8, IL-10 , IL-12 p35, IL-12 p40, macrophage inflammatory protein-1 alpha, granulocyte/macrophage-CSF, granulocyte-CSF, IFN-alpha, and TNF alpha by monocytes activated with LPS
Tilg et al., Cytokine 1995 (Neoplasms) : Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy
Benveniste et al., Proc Natl Acad Sci U S A 1996 (Acute Disease...) : Comparative interleukin ( IL-2 ) /interferon IFN-gamma and IL-4/IL-10 responses during acute infection of macaques inoculated with attenuated nef truncated or pathogenic SICmac251 virus
Kimata et al., J Exp Med 1996 : Histamine increased IL-10 and IL-6 production without affecting IL-10 and IL-6 receptor expression, in cultures with IL-4 plus anti-CD58 mAb and with IL-13 plus anti-CD58 mAb, respectively, which was blocked by thioperamide and dimaprit, respectively
Venkataraman et al., Cryobiology 1996 : X. Decrease in interleukin-12 production by frozen human peripheral blood mononuclear cells is mediated by the endogenously hypersecreted interleukin-10
Paysant et al., Br J Haematol 1998 : The increase in uPA suggests that IL-4 and IL-13 could induce plaque fissuring by monocytes, whereas IL-10 may induce protection against matrix protein degradation by decreasing uPA
Fulton et al., J Infect Dis 1998 : Regulation of interleukin-12 by interleukin-10 , transforming growth factor-beta, tumor necrosis factor-alpha, and interferon-gamma in human monocytes infected with Mycobacterium tuberculosis H37Ra
Pai et al., Oncol Res 1998 : Differential effect of interleukin 10 on interleukin 12- and interleukin 2-mediated killer induction from blood mononuclear cells