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FGF2 — NFKB1

Text-mined interactions from Literome

Hoshi et al., J Biol Chem 2000 : Thrombin receptor activating peptide ( TRAP ) and basic fibroblast growth factor (bFGF) stimulated SMC proliferation and rapidly enhanced the NF-kappaB transcriptional activity in a dose dependent manner ... NF-kappaB was activated after the stimulation of TRAP, bFGF, and TNF-alpha in electrophoretic mobility shift assay, and E5510 suppressed the NF-kappaB activation induced by TRAP and bFGF but not the activation by TNF-alpha ... These results indicate that TRAP and bFGF induced I-kappaB degradation and NF-kappaB activation through a distinct pathway from TNF-alpha and that ERK1/2 may play an important role in NF-kappaB activation induced by TRAP and bFGF
Bushdid et al., Dev Biol 2001 : NF-kappaB mediates FGF signal regulation of msx-1 expression ... These results suggest that NF-kappaB mediates the FGF-2/-4 signal regulation of msx-1 gene expression
Ramana et al., J Biol Chem 2002 : Inhibition of AR in VSMC also prevented the activation of NF-kappa B by basic fibroblast growth factor (bFGF) , angiotensin-II (Ang-II), and platelet derived growth factor ( PDGF-AB )
Wakisaka et al., Cancer Res 2002 : These results suggest that FGF-2 release is independently mediated by NF-kappaB signaling, not simply a consequence of induction itself ... Thus, NF-kappaB signaling is involved in induction of expression and release of FGF-2 by LMP1
Tang et al., J Hand Surg Am 2003 (Tendon Injuries) : Expression levels of type I collagen and NF-kappaB genes of tenocytes were increased significantly by bFGF ... Results of this study show that expression of type I collagen and NF-kappaB genes is promoted manifestly by bFGF
Lu et al., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2003 : bFGF stimulated the EC proliferation and enhanced the expression of NF-kappa B and ki-67 in nucleus ; TNP-470 and Dex suppressed EC proliferation induced by bFGF, and reduced the expression of NF-kappa B and ki-67 in nucleus
Tang et al., Plast Reconstr Surg 2004 : Expression levels of NIK, IKKalpha, IKKbeta, and NF-kappaB genes were significantly increased by bFGF at concentrations of 2 and 10 ng/ml. Western blot confirmed the increase of NF-kappaB in the tenocytes
Tanaka et al., J Pharmacol Exp Ther 2005 : We found that parthenolide could effectively inhibit the gene expression mediated by NF-kappaB and the production of bFGF and MMP-1 from cells overexpressing p65, a major subunit of NF-kappaB
Wang et al., Plastic and reconstructive surgery 2006 : Transfer of exogenous PDGF gene to ischemic flaps promotes expression of VEGF and bFGF genes and activation of NF-kappaB gene in addition to its effects on the PDGF gene
Flati et al., Int J Immunopathol Pharmacol 2006 : Furthermore, we found that bFGF inhibits the TNF mediated activation of NF-kappaB by blocking phosphorylation and degradation of IkappaBalpha
Yang et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Lastly, we examined the role of the immediate-early transcription factors AP-1 and NF-kappaB and have found that phospholipase C-gamma dependent c-Jun and ERK dependent c-fos, but not the NF-kappaB , are strongly activated by bFGF , which in turn regulates the neuronal differentiation of BMSCs
Crisostomo et al., Am J Physiol Cell Physiol 2008 : VEGF, FGF2 , and HGF expression was significantly reduced by NF kappa B inhibition ( 50 % decrease ) but not ERK or JNK inhibition ... VEGF, FGF2 , and HGF expression was significantly reduced by NF kappa B inhibition ( 50 % decrease ) but not ERK or JNK inhibition
Tanaka et al., Curr Drug Metab 2010 : We found that either parthenolide or magnolol could effectively inhibit the gene expression mediated by NF-kappaB and the production of bFGF and MMP-1 from cells overexpressing p65, a major subunit of NF-kappaB