Gene interactions and pathways from curated databases and text-mining

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GJC2 — VEGFA

Text-mined interactions from Literome

Suarez et al., J Cell Sci 2001 : VEGF maximally blocked GJC 15 minutes after growth factor administration ... The function of VEGF mediated disruption of GJC might be to restrict an increase in endothelium permeability to the environment affected by local injury to blood vessels
Thuringer et al., Ann N Y Acad Sci 2004 : Dye coupling experiments revealed that BK or VEGF completely blocked GJC ... We conclude that VEGF induced disruption of GJC via Cx43 remodeling is relayed by an autocrine communication via secretion of ATP to preserve intercellular Ca ( 2+ ) signaling in capillary endothelium