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CDK2 — DAP

Text-mined interactions from Literome

Frolov et al., Genes Dev 2003 : Here we show that the cell cycle defects of dE2F1 depleted cells depend on the cooperative effects of dE2F2 and DACAPO (DAP) , an inhibitor of Cyclin E/cyclin dependent kinase 2 ( CycE/cdk2 )
He et al., Oncogene 2005 : Conversely, inhibition of p21 induction by cycloheximide or by p21 gene deletion prevents DAP induced inhibition of Cdk4 and Cdk2 activities
He et al., Br J Cancer 2006 : We have now evaluated the role of another CDK inhibitor p27 as a contributor to DAP mediated inhibition of G1-phase CDK2 activity
Sukhanova et al., BMC developmental biology 2008 : Our data demonstrate that Cyclin E/Cdk2 kinase activity is absolutely required for S phase in SMW, and that Dap is required for the proper cell cycle arrest of cells exiting the SMW