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TNF — TNFRSF6B
Text-mined interactions from Literome
Yang et al., Cell Death Differ 2004
(Bone Resorption) :
Consistent with the abrogation of osteoclastogenic effect of DcR3 by TNFR-Fc,
DcR3 treatment can
induce osteoclastogenic cytokine
TNF-alpha release through ERK and p38 MAPK signaling pathways
Hayashi et al., Arthritis Rheum 2007
(Arthritis, Rheumatoid...) :
DcR3 is mostly expressed in tumor cells, and it competitively
inhibits binding of
TNF to TNFRs ...
TNFalpha increased
DcR3 expression and inhibited Fas induced apoptosis in RA FLS, but not in OA FLS ...
DcR3 expressed in RA FLS is
increased by
TNFalpha and protects the cells against Fas induced apoptosis