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NFKB1 — UBE2N

Pathways - manually collected, often from reviews:

• WikiPathways Interleukin-1 Induced Activation of NF-kappa-B: Complex of AJUBA-PRKCZ-TIFA-SQSTM1-UBE2N-UBE2V1-TRAF6-IRAK1 → NFKB1 (activation)
• WikiPathways Simplified Depiction of MYD88 Distinct Input-Output Pathway: Complex of TRAF6-TIFA-IRAK1-UBE2N-UBE2V1 → NFKB1 (activation)

Text-mined interactions from Literome

Luftig et al., Proc Natl Acad Sci U S A 2003 : Consistent with the importance of TRAF6, LMP1 induced NF-kappaB activation in HEK293 cells was inhibited by expression of dominant negative TAB2 and Ubc13 alleles
Andersen et al., J Cell Biol 2005 : Functionally, we describe that Ubc13-Mms2 is required for DNA damage repair but not nuclear factor kappaB (NF-kappaB) activation, whereas Ubc13-Uev1A is involved in NF-kappaB activation but not DNA repair ... Functionally, we describe that Ubc13-Mms2 is required for DNA damage repair but not nuclear factor kappaB (NF-kappaB) activation, whereas Ubc13-Uev1A is involved in NF-kappaB activation but not DNA repair
Shembade et al., J Virol 2007 : Collectively, our results reveal that Ubc13 is essential for Tax ubiquitination, its interaction with NEMO, and Tax mediated NF-kappaB activation
Yang et al., J Biol Chem 2007 (Tuberculosis) : We also demonstrate a requirement for the E2-conjugating enzyme Ubc13 , the E3 ubiquitin ligase Traf6, and the ubiquitin activated kinase Tak1 in Nod2 mediated NF-kappaB activation