◀ Back to EIF4G1
EIF4G1 — RPTOR
Text-mined interactions from Literome
Prabhu et al., Oncogene 2007
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Experiments with rapamycin and the Bcr-Abl inhibitor, imatinib mesylate, in Bcr-Abl expressing cell lines and primary CML cells indicated that Bcr-Abl and
mTORC1 induced formation of the translation initiation complex,
eIF4F
Grosso et al., PloS one 2011
:
In spite of this,
mTORc1 inhibition
reduces eIF4F complex formation, and depresses translocation of TOP mRNAs on polysomes