Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Wadsworth et al., Biochem Pharmacol 1999 : Unexpectedly, the wine polyphenolics quercetin and resveratrol and the antioxidant N-acetylcysteine (NAC) did not inhibit LPS induced activation of the NF-KB complex p50/65 , as determined by mobility shift
Shimizu et al., Am J Physiol Cell Physiol 2013 : Both NAC and DPI suppressed indoxyl sulfate induced expression of NF-?B p65 and CREB
Qiu et al., Vet Immunol Immunopathol 2013 : AAP ( 0.125-1.0mM ) and NAC ( 0.0625-1.0mM ) down-regulate the expression of cytokines and inhibit NF-?B p65 protein transfer from the cytoplasm to the nucleus in vitro
Hann et al., J Exp Clin Cancer Res 2013 : NAC induced p53 and reduced p65 protein expression through activation of PPARa