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MYC — PRL

Text-mined interactions from Literome

Domínguez-Cáceres et al., Oncogene 2004 : Prolactin induces c-Myc expression and cell survival through activation of Src/Akt pathway in lymphoid cells ... In contrast, PD184352 did not alter PRL activation of c-Myc mRNA expression or stimulation of p70S6K, Akt, and the Jak2/Stat5 pathway ... Furthermore, transient expression of nonphosphorylatable FKHRL1-A3 mutant impaired PRL induced activation of the c-Myc promoter
González et al., Oncogene 2009 (Breast Neoplasms) : Finally, PRL induces expression of c-Myc and Cyclin D1 and leads to increased cell proliferation, which is specifically antagonized by ICI 182,780 or ERalpha depletion