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TNF — TTF1

Text-mined interactions from Literome

Ohmori et al., Endocrinology 1999 : The suppressive effect of TNF-alpha on TTF-1-DNA complex formation is, in part, caused by suppression of TTF-1 gene transcription by TNF-alpha
Das et al., Am J Physiol Lung Cell Mol Physiol 2011 (Respiratory Distress Syndrome, Adult) : In this study, we identified functionally important transcription factor binding sites in the TTF-1 proximal promoter and studied tumor necrosis factor-a (TNF-a) regulation of TTF-1 expression ... TNF-a inhibited TTF-1 but not Sp1 or hepatocyte nuclear factor-3 DNA binding to TTF-1 promoter ... Transactivation experiments in A549 cells indicated that TNF-a inhibited TTF-1 promoter activation by exogenous Sp1 and TTF-1 without altering their levels, suggesting inhibition of transcriptional activities of these proteins