Verschelde et al., Cell Death Differ 2003
:
Activation of CD4 ( + ) or CD8 ( + ) T cells by antigenic peptides induced an early but transient IL-2 independent expression of A1 and Bcl-xl mRNA and proteins, whereas expression of Bcl-2 was delayed and required IL-2
Wojciechowski et al., J Exp Med 2007
(Lymphocytic Choriomeningitis) :
In vivo, naive CD8 ( + ) T cells required Bcl-2 to combat Bim to maintain peripheral survival, whereas naive CD4 ( + ) T cells did not
Vranjkovic et al., J Leukoc Biol 2011
(HIV Infections) :
In contrast, IL-7 induced Bcl-2 expression was not impaired in CD8 ( + ) CD127 ( + ) T cells from HIV ( + ) individuals