Gene interactions and pathways from curated databases and text-mining

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NOX3 — PTPN11

Text-mined interactions from Literome

Sampaio et al., Hypertension 2007 : Ang II-induced phosphorylation of c-Src, extracellular signal regulated kinase ( ERK ) 1/2, and SHP-2 and activation of NAD ( P ) H oxidase were assessed in the absence and presence of Ang- ( 1-7 ) ( 10 ( -6 ) mol/L, 15 minutes ) by immunoblotting and lucigenin enhanced chemiluminescence, respectively
Tabet et al., Circ Res 2008 (Hypertension) : Ang II increased SHP-2 phosphorylation and activity with blunted responses in SHRs. Ang II-induced SHP-2 effects were inhibited by valsartan ( AT(1)R blocker ), apocynin ( NAD ( P ) H oxidase inhibitor ), and Nox1 siRNA