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NOD1 — TLR2
Text-mined interactions from Literome
Watanabe et al., Nat Immunol 2004
(Crohn Disease) :
Moreover,
NOD2 deficiency or the presence of a Crohn disease-like Card15 mutation
increased Toll-like receptor 2-mediated activation of NF-kappa B-c-Rel, and T ( H ) 1 responses were enhanced
van Heel et al., Eur J Immunol 2005
:
NOD1 activation by low nanomolar concentrations of the specific muropeptide ligand M-TriDAP induced minimal human peripheral blood mononuclear cell TNF-alpha, IL-1beta or IL-10 secretion, but synergistically
increased Toll-like receptor ( TLR ) -induced responses