Gene interactions and pathways from curated databases and text-mining

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NOD1 — TLR2

Text-mined interactions from Literome

Watanabe et al., Nat Immunol 2004 (Crohn Disease) : Moreover, NOD2 deficiency or the presence of a Crohn disease-like Card15 mutation increased Toll-like receptor 2-mediated activation of NF-kappa B-c-Rel, and T ( H ) 1 responses were enhanced
van Heel et al., Eur J Immunol 2005 : NOD1 activation by low nanomolar concentrations of the specific muropeptide ligand M-TriDAP induced minimal human peripheral blood mononuclear cell TNF-alpha, IL-1beta or IL-10 secretion, but synergistically increased Toll-like receptor ( TLR ) -induced responses