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RAC1 — RBL2
Text-mined interactions from Literome
Ceacareanu et al., Am J Physiol Cell Physiol 2006
:
We report that IGF-I induces phosphorylation of
p130 ( cas ) and
activation of
Rac1 and that NO attenuates these effects
Sharma et al., BMC cell biology 2008
:
Phosphorylation of
p130Cas initiates
Rac activation and membrane ruffling ... Phosphorylation of
p130Cas in SYF cells
led to activation of
Rac1 and increased membrane ruffling and lamellipodium formation, events associated with cell migration
Liu et al., J Biol Chem 2009
(Breast Neoplasms) :
We further determined that suppression of expression of Cdc42, Ack1,
p130 ( Cas ), or Crk
reduces Rac1 activation and cell motility in Dbs expressing cells to a level comparable with that in vector cells
Gupta et al., J Cell Sci 2009
:
We found for the first time that specific ligation of integrin alpha9beta1 rapidly activates Src tyrosine kinase, with concomitant tyrosine phosphorylation of
p130Cas and
activation of
Rac-1
Vanden Borre et al., Cell Signal 2011
:
Using R743A BCAR3, a point mutant that has lost the ability to bind p130Cas, we find that
BCAR3-p130Cas complex formation is not
required for BCAR3 mediated anti-estrogen resistance,
Rac activation or discohesion of epithelial breast cancer cells
Kiyokawa et al., Genes Dev 1998
:
Coexpression of CrkII and
p130 ( Cas )
enhanced this DOCK180 dependent activation of
Rac1